Neonatal Extravasation
Neonatal Extravasation
Nitroglycerin 2% is an option to treat extravasations. Nitroglycerin acts to relax smooth muscle resulting in arteriolar, arterial and venous vasodilation that results in increased capillary blood flow, counteracting the effects of vasoactive medications. This will help to reverse tissue ischemia and cell death. In the neonatal population, there is a case report describing the use of 1 inch of 2% nitroglycerin ointment for treatment of a dopamine extravasation, located in the dorsum of the left hand, in a 1.8 kg 34 week preemie. This resulted in return of circulation within a few minutes. Of note, treatment was started almost 12 hours after the extravasation was initially noted and patient had no significant change in hemodynamics.
Nitroglycerin Ointment (2%)
Nitroglycerin 2% is an option to treat extravasations. Nitroglycerin acts to relax smooth muscle resulting in arteriolar, arterial and venous vasodilation that results in increased capillary blood flow, counteracting the effects of vasoactive medications. This will help to reverse tissue ischemia and cell death. In the neonatal population, there is a case report describing the use of 1 inch of 2% nitroglycerin ointment for treatment of a dopamine extravasation, located in the dorsum of the left hand, in a 1.8 kg 34 week preemie. This resulted in return of circulation within a few minutes. Of note, treatment was started almost 12 hours after the extravasation was initially noted and patient had no significant change in hemodynamics.
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