Long-term Steroid Therapy Impacts Cardiac Fat Deposition

Conclusions

The present data suggest that the use of steroids in patients with different rheumatic disorders is associated with increased cardiac adipose tissue accumulation. This effect seems to be stronger in patients with high-dose prednisone equivalent doses (>7.5 mg daily for at least 6 months) than in patients with low-dose prednisone equivalent doses, suggesting a cumulative dose-dependent effect.