Hormones and Dry Eye Syndrome
Hormones and Dry Eye Syndrome
We describe here the current knowledge base pertaining to the role of some hormonal imbalances in DES initiation and progression. Clinical findings and pathophysiological mechanisms confirm the associations between diabetes mellitus, estrogen level declines, and thyroid gland diseases and DES. Very promising preliminary results obtained in several animal models are described for employing gene therapy as a novel alternative to improve treatment of hormone related DES.
Conclusion
We describe here the current knowledge base pertaining to the role of some hormonal imbalances in DES initiation and progression. Clinical findings and pathophysiological mechanisms confirm the associations between diabetes mellitus, estrogen level declines, and thyroid gland diseases and DES. Very promising preliminary results obtained in several animal models are described for employing gene therapy as a novel alternative to improve treatment of hormone related DES.
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