Antioxidant Levels Key to Prostate Cancer Risk in Some Men
Prostate cancer was determined to be 75% less frequent in Caucasian males with higher levels of selenium, Vitamin E and carotenoid lycopene.
(US Study) By the same token if carriers of a particular genetic variation sensitive to oxidative stress display low levels of these vitamins are a lot more prone to developing prostate cancer.
These studies also point out that oxidative stress is an important factor in prostate cancer development and progression hence an optimum antioxidant supplements (selenium, Vitamin E, Lycopene) serves as a great way of preventing prostate cancer.
The study was conducted on a group of 567 men suffering from prostate cancer and 764 cancer-free men between 1982 and 1995.
Initially the study purpose was to determine the effects of aspirin and beta-carotene on male's health.
Dr.
Haojie Li (researcher at Brigham, Women's Hospital and Havard Medical School) checked how variant of the gene act as antioxidants defending the human cells against cancer.
The gene called MnSOD is inherited by children from the parent in three forms: VV, VA AA.
The men in the study carried the genotypes as follows: 25% AA, 25% VV, 50% VA.
Between men having one of the three forms of gene the ones with AA genotype appeared to be more sensitive to the status of the antioxidants and therefore more prone to prostate cancer if their antioxidants levels are below average.
Te carriers of the other two MnSOD types, VA and VV respectively, are equally exposed to the risk of developing the disease independent of their antioxidants levels in their bodies.
If Selenium was at a low level MnSOD AA males had an over 88% higher risk of developing this type of cancer compared with the MnSOD VA or VV males.
If the selenium levels in blood were high MnSOD AA males had a 65% less risk of developing prostat cancer than the other males.
Both results weren't based on extreme levels of selenium according with Dr.
Li.
Similar results were determined for lycopene and Vitamin E in separate tests.
A higher risk was determined in men with high levels of all three antioxidants together.
The risk of cancer was significantly higher in males with the MnSOD AA genotype when looking at high versus low antioxidants levels.
Natural dietary intake looks like a factor with positive impact in reducing the risk of prostate cancer.
Tomatoes (for lycopene intake) and supplements for Vitamin E and/or selenium) are only a couple of great sources of antioxidants thus ways to reduce the risk.
The same connection was researched and demonstrated for risk of developing breast cancer.
This condition reached high numbers in the last years going as high as 500,000 new cases every year and these figures are on the rise as aging populations grows.
(US Study) By the same token if carriers of a particular genetic variation sensitive to oxidative stress display low levels of these vitamins are a lot more prone to developing prostate cancer.
These studies also point out that oxidative stress is an important factor in prostate cancer development and progression hence an optimum antioxidant supplements (selenium, Vitamin E, Lycopene) serves as a great way of preventing prostate cancer.
The study was conducted on a group of 567 men suffering from prostate cancer and 764 cancer-free men between 1982 and 1995.
Initially the study purpose was to determine the effects of aspirin and beta-carotene on male's health.
Dr.
Haojie Li (researcher at Brigham, Women's Hospital and Havard Medical School) checked how variant of the gene act as antioxidants defending the human cells against cancer.
The gene called MnSOD is inherited by children from the parent in three forms: VV, VA AA.
The men in the study carried the genotypes as follows: 25% AA, 25% VV, 50% VA.
Between men having one of the three forms of gene the ones with AA genotype appeared to be more sensitive to the status of the antioxidants and therefore more prone to prostate cancer if their antioxidants levels are below average.
Te carriers of the other two MnSOD types, VA and VV respectively, are equally exposed to the risk of developing the disease independent of their antioxidants levels in their bodies.
If Selenium was at a low level MnSOD AA males had an over 88% higher risk of developing this type of cancer compared with the MnSOD VA or VV males.
If the selenium levels in blood were high MnSOD AA males had a 65% less risk of developing prostat cancer than the other males.
Both results weren't based on extreme levels of selenium according with Dr.
Li.
Similar results were determined for lycopene and Vitamin E in separate tests.
A higher risk was determined in men with high levels of all three antioxidants together.
The risk of cancer was significantly higher in males with the MnSOD AA genotype when looking at high versus low antioxidants levels.
Natural dietary intake looks like a factor with positive impact in reducing the risk of prostate cancer.
Tomatoes (for lycopene intake) and supplements for Vitamin E and/or selenium) are only a couple of great sources of antioxidants thus ways to reduce the risk.
The same connection was researched and demonstrated for risk of developing breast cancer.
This condition reached high numbers in the last years going as high as 500,000 new cases every year and these figures are on the rise as aging populations grows.
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